Author Archives: andrearobinson2014

Minimizing Mitogenic Potency of Insulin Analogues Through Modification of a Disulfide Bond

Authors Shee Chee Ong, Alessia Belgi, Allanah L Merriman, Carlie A Delaine, Bianca Van Lierop, Sofianos Andrikopoulos, Andrea J Robinson, Briony E Forbes Published Frontiers in Endocrinology Graphical abstract   Abstract The mechanisms by which insulin activates the insulin receptor … Continue reading

Posted in Publications 2022 | Leave a comment

Toward the stereoselective synthesis of zaragozic acid framework: A desilylation-aldol reaction approach

Authors Yudhi D. Kurniawan, Kellie L. Tuck, Sergio Castillón, Andrea J. Robinson Published Tetrahedron Letters Graphical abstract Abstract A convergent synthesis of the C3-C8 fragment of zaragozic acids is described. The key reactions include desilylation-aldol reaction, rearrangement induced by regioselective reductive cleavage, … Continue reading

Posted in Publications 2019 | Leave a comment

[18 F]Ethenesulfonyl Fluoride as a Practical Radiofluoride Relay Reagent

Authors Bo Zhang, Benjamin H. Fraser, Mitchell A. Klenner, Zhen Chen, Steven H. Liang, Massimiliano Massi, Andrea J. Robinson, Giancarlo Pascali Published Chemistry – A European Journal Graphical abstract Abstract Fluorine-18 is the most utilized radioisotope in positron emission tomography … Continue reading

Posted in Publications 2019 | Leave a comment

Bioinspired carrier-free peptide conjugated BF2-oxasmaragdyrin dye-based nano self-assemblies: a photostable NIR cancer theragnostic agent

Authors Kandala Laxman, B. Pradeep K. Reddy, Sumit K. Mishra, Andrea Robinson, Abhijit De, Rohit Srivastava, Mangalampalli Ravikanth Published NPG Asia Materials Graphical abstract   Abstract Photothermal therapy (PTT) has attracted great interest in cancer treatment, and the quest for potential … Continue reading

Posted in Publications 2020 | Leave a comment

Design, Development, In Vitro and Preliminary In Vivo Evaluation of a Novel Photo-Angioplasty Device: Lumi-Solve

Authors HongBin Liu, Gopal R. Sama, Andrea Robinson, Simon Mountford, Philip E. Thompson, Andrew Rodda, John Forsythe, Patrick J. Mornane, Paul Pasic, Helmut Thissen, Melissa Byrne, David M. Kaye & Anthony E. Dear  Published Cardiovascular Engineering and Technology Graphical abstract   Abstract Purpose Paclitaxel (PTX)-coated drug eluting balloon catheters (DEBc) used in … Continue reading

Posted in Publications 2021 | Leave a comment

BF2-Oxasmaragdyrin Nanoparticles: A Non-toxic, Photostable, Enhanced Non-radiative Decay-Assisted Efficient Photothermal Cancer Theragnostic Agent

Authors Kandala Laxman, B. Pradeep K. Reddy, Sumit K. Mishra, Maddala Bala Gopal, Andrea Robinson, Abhijit De,  Rohit Srivastava, Mangalampalli Ravikanth Published ACS Appl. Mater. Interfaces Graphical abstract Abstract Photothermal therapy (PTT), a simple and minimally invasive procedure, is an attractive … Continue reading

Posted in Publications 2020 | Leave a comment

Synthesis and Studies of Glucosamine Conjugated BF2 -Oxasmaragdyrin

Authors Kandala Laxman, B. Pradeep K. Reddy, Andrea Robinson, Rohit Srivastava, Mangalampalli Ravikanth Published ChemistrySelect Graphical abstract Abstract A value addition to the existing NIR fluorescence imaging agents has been synthesized in the form of glucosamine conjugated BF2-oxasmaragdyrin by treating … Continue reading

Posted in Publications 2020 | Leave a comment

Cell-Penetrating Peptide-Conjugated BF 2 -Oxasmaragdyrins as NIRF Imaging and Photothermal Agents”

Authors Kandala Laxman, B. Pradeep K. Reddy, Andrea Robinson, Rohit Srivastava, Mangalampalli Ravikanth Published ChemMedChem Graphical abstract Abstract Cell-penetrating peptides (CPPs) are excellent cell internalizing agents for hydrophobic drug/dye moieties. We exploited this property of CPPs for the cell internalization … Continue reading

Posted in Publications 2020 | Leave a comment

α-Conotoxin Peptidomimetics: Probing the Minimal Binding Motif for Effective Analgesia

Authors Adam C. Kennedy, Alessia Belgi, Benjamin W. Husselbee, David Spanswick, Ray S. Norton, Andrea J. Robinson Published Toxins Graphical abstract   Abstract Several analgesic α-conotoxins have been isolated from marine cone snails. Structural modification of native peptides has provided … Continue reading

Posted in Conotoxins, Publications 2020 | Leave a comment

Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models

Authors Alessia Belgi, James V. Burnley, Christopher A. MacRaild, Sandeep Chhabra, Khaled A. Elnahriry, Samuel D. Robinson, Simon G. Gooding, Han-Shen Tae, Peter Bartels, Mahsa Sadeghi, Fei-Yue Zhao, Haifeng Wei, David Spanswick, David J. Adams, Ray S. Norton, Andrea. J. … Continue reading

Posted in Conotoxins, Publications 2021 | Leave a comment