Authors |
Ellen C. Gleeson, Zhen J. Wang, W. Roy Jackson, and Andrea J. Robinson |
Published | Journal of Organic Chemistry |
Graphical abstract |
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Abstract |
A simple and generic approach to access a new family of Ru−alkylidene olefin metathesis catalysts with specialized properties is reported. This strategy utilizes a late stage, utilitarian Hoveyda-type ligand derived from tyrosine, which can be accessed via a multigram-scale synthesis. Further functionalization allows the catalyst properties to be tuned, giving access to modified second-generation Hoveyda−Grubbs-type catalysts. This divergent synthetic approach can be used to access solid-supported catalysts and catalysts that function under solvent-free and aqueous conditions. |
Citation |
Ellen C. Gleeson, Zhen J. Wang, W. Roy Jackson, and Andrea J. Robinson, J. Org. Chem., 2015, 80(14), 7205–7211 |
Article | |
Doi | 10.1021/acs.joc.5b01091 |
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