Tag Archives: dicarba peptides

A one-pot selective homodimerisation/hydrogenation strategy for sequential dicarba bridge formation

Authors James Burnley, W. Roy Jackson and Andrea J. Robinson Published Journal of Organic Chemistry Graphical abstract   Abstract The installation of interlocked dicarba bridges into peptide sequences requires the development of regioselective and chemoselective methodology. This manuscript describes a one-pot, … Continue reading

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A Concise Cross-Metathesis Route to Enantiopure 1-Azaspirocycles

Authors Zhen James Wang, Nicolas Daniel Spiccia, Christopher James Gartshore, Jayamini Illesinghe, William Roy Jackson and Andrea Jane Robinson Published Synthesis Graphical abstract   Abstract The 1-azaspirocyclic ring system can be found in a number of bioactive natural product families. … Continue reading

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Combinatorial Approach for the Rapid Determination of Thermochromic Behavior of Binary and Ternary Cholesteric Liquid Crystalline Mixtures

Authors Louise C. van der Werff, Andrea J. Robinson and Ilias L. Kyratzis Published ACS Combinatorial Science Graphical abstract   Abstract A combinatorial approach was developed for the rapid 
determination of thermochromic behavior of a large number of binary 
and … Continue reading

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A one pot, metathesis–hydrogenation sequence for the selective formation of carbon–carbon bonds

Authors Andrea J. Robinson, Jomana Elaridi, Jim Patel and W. Roy Jackson Published Chemical Communications Graphical abstract   Abstract The selective formation of C–C bonds in complex molecules is one of the major challenges in organic chemistry. Olefin metathesis provides … Continue reading

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